Taking popular heartburn drugs for prolonged periods has been linked to serious kidney problems, including kidney failure. The sudden onset of kidney problems often serves as a red flag for doctors to discontinue their patients''t experience acute kidney problems beforehand, meaning patients may not be aware of a decline in kidney function, according to researchers at Washington University School of Medicine in St. Louis and the Veterans Affairs St. Louis Health Care System. Therefore, people who take PPIs, and their doctors, should be more vigilant in monitoring use of these medications.
The study is published Feb. 22 in Kidney International.
The onset of acute kidney problems is not a reliable warning sign for clinicians to detect a decline in kidney function among patients taking proton pump inhibitors, said Ziyad Al-Aly, MD, the study''s care.
The researchers -- including first author Yan Xie, a biostatistician at the St. Louis VA -- analyzed data from the Department of Veterans Affairs databases on 125,596 new users of PPIs and 18,436 new users of other heartburn drugs referred to as H2 blockers. The latter are much less likely to cause kidney problems but often aren''s associate chief of staff for research and education and co-director of the VA''silent''t experience acute kidney problems beforehand. ScienceDaily. Retrieved May 6, 2020 from www.sciencedaily.com/releases/2017/02/170222082252.htm
Washington University in St. Louis. "" ScienceDaily. www.sciencedaily.com/releases/2017/02/170222082252.htm (accessed May 6, 2020).