Description and Brand Names
Drug information provided the 1 last update 08 Jul 2020 by: IBM MicromedexDrug information provided by: IBM Micromedex
US Brand Name
- First - Omeprazole
- PriLOSEC OTC
Omeprazole is used to treat certain conditions where there is too much acid in the stomach. It is used to treat gastric and duodenal ulcers, erosive esophagitis, and gastroesophageal reflux disease (GERD). GERD is a condition where the acid in the stomach washes back up into the esophagus. Sometimes omeprazole is used in combination with antibiotics (eg, amoxicillin, clarithromycin) to treat ulcers associated with the infection caused by the H. pylori bacteria.
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Omeprazole is also used to treat dyspepsia, a condition that causes sour stomach, belching, heart burn, or indigestion.
In addition, omeprazole is used to prevent upper gastrointestinal tract bleeding in seriously ill patients.
Omeprazole is a proton pump inhibitor (PPI). It works by decreasing the amount of acid produced by the stomach.
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Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems the 1 last update 08 Jul 2020 may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
- Diarrhea or
- Hypomagnesemia (low magnesium in the blood), history of or
- Osteoporosis (bone problem) or
- Seizures, history of or
- Systemic lupus erythematosus (SLE)—Use with caution. May make these conditions worse.
- Liver disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.
Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If you are using this medicine without a the 1 last update 08 Jul 2020 prescription, follow the instructions on the medicine label. Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If you are using this medicine without a prescription, follow the instructions on the medicine label.
This medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions.
Take omeprazole capsules or delayed-release capsules before a meal, preferably in the morning. Omeprazole tablets may be taken with food or on an empty stomach. Take omeprazole powder for oral suspension on an empty stomach at least 1 hour before a meal. For patients receiving continuous feeding through a tube, feeding should be temporarily stopped about 3 hours before and 1 hour after administration of omeprazole powder for oral suspension.
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If you are taking this medicine to treat an ulcer that is associated with an H. pylori infection, take it together with antibiotics (eg, amoxicillin, clarithromycin) at the same time of day.
Swallow the capsule and tablet forms of omeprazole whole. Do not open the capsule. Do not crush, break, or chew the capsule or the tablet.
If you cannot swallow the omeprazole delayed-release capsules, you may open it and sprinkle the pellets contained in the capsule on one tablespoon of applesauce. This mixture must be swallowed immediately with a glass of cool water. The applesauce should not be hot and should be soft enough to be swallowed without chewing. Do not chew or crush the pellets.
To use the powder for oral suspension:
- Empty packet of powder into a small cup containing 2 tablespoons of water.
- Do not use other liquids or foods.
- Stir well and drink immediately.
- Refill cup with water and drink.
To use the delayed-release oral suspension:
- Empty the contents of a 2.5 milligrams (mg) packet of powder into a container containing 5 mL of water.
- Empty the contents of a 10 mg packet of powder into a container containing 15 mL of water.
- Do not use other liquids or foods.
- Stir and leave it for 2 to 3 minutes to thicken.
- Stir well and drink within 30 minutes.
- If any medicine remains after drinking, add more water, stir, and drink immediately.
If you are using the delayed-release oral suspension with a nasogastric or gastric tube:
- Add 5 mL to a catheter tipped syringe and then add the contents of a 2.5 mg packet (or 15 mL of water for the 10 mg packet).
- Shake the syringe right away and leave it for 2 to 3 minutes to thicken.
- Shake the syringe and give the medicine through the nasogastric or gastric tube into the stomach with 30 minutes.
- Refill the syringe with an equal amount of water.
- Shake and flush any remaining contents from the nasogastric or gastric tube into the stomach.
The dose of this medicine will be different for different patients. Follow your doctor''s progress at regular visits. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it. Blood, urine, and other laboratory tests may be needed to check for unwanted effects. If your or your child''s wort) or vitamin supplements.
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any the 1 last update 08 Jul 2020 of the following side effects occur:Check with your doctor immediately if any of the following side effects occur:
- Back, leg, or stomach pain
- bleeding or crusting sores on the lips
- bloody or cloudy urine
- continuing ulcers or sores in the mouth
- difficult, burning, or painful urination
- frequent urge to urinate
- general feeling of discomfort or illness
- itching, skin rash
- joint pain
- loss of appetite
- muscle aches or cramps
- red or irritated eyes
- redness, tenderness, itching, burning, or peeling of the skin
- sore throat
- sores, ulcers, or white spots on the lips, in the mouth, or on the genitals
- unusual bleeding or bruising
- unusual tiredness or weakness
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- Blistering, peeling, or loosening of the skin
- fast, racing, or uneven heartbeat
- mood or mental changes
- muscle spasms (tetany) or twitching seizures
- red skin lesions, often with a purple center
- red, irritated eyes
Get emergency help immediately if any of the following symptoms of overdose occur:
Symptoms of overdose
- Blurred vision
- dryness of the mouth
- increased sweating
Some side effects may occur that usually do not need medical attention. These side the 1 last update 08 Jul 2020 effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
- Body aches or pain
- chest pain
- diarrhea or loose stools
- difficulty with breathing
- ear congestion
- loss of voice
- muscle pain
- nasal congestion
- runny nose
- unusual drowsiness
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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Original article: https://www.mayoclinic.org/drugs-supplements/omeprazole-oral-route/side-effects/drg-20066836
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